Annual report pursuant to Section 13 and 15(d)

Equity Incentive Plan (Details)

v3.23.1
Equity Incentive Plan (Details) - $ / shares
12 Months Ended
Dec. 31, 2022
Dec. 31, 2021
Dec. 31, 2020
Number of Options      
Outstanding at beginning of year (in shares) 12,954 6,249  
Granted (in shares) 78,641 8,654  
Expired (in shares) (14) (825)  
Forfeited (in shares) (6,830) (1,124)  
Outstanding at end of year (in shares) 84,751 12,954 6,249
Exercisable at end of year (in shares) 4,939 5,087  
Vested and expected to vest at end of year (in shares) 84,751 12,954  
Weighted Average Exercise Price      
Outstanding at beginning of year (in usd per share) $ 426.25 $ 840.88  
Granted (in usd per share) 8.49 164.30  
Expired (in usd per share) 842.57 1,046  
Forfeited (in usd per share) 446.34 259.70  
Outstanding at end of year (in usd per share) 36.92 426.25 $ 840.88
Exercisable at end of year (in usd per share) 442.52 847.31  
Vested and expected to vest at end of year (in usd per share) $ 36.92 $ 426.25  
Weighted Average Contractual Life      
Outstanding 9 years 7 months 2 days 5 years 6 months 21 days 2 years 3 months 18 days
Exercisable at end of year 7 years 3 months 7 days 3 years 1 month 2 days  
Vested and expected to vest at end of year 9 years 7 months 2 days 5 years 6 months 21 days