Annual report pursuant to Section 13 and 15(d)

Equity Incentive Plan (Tables)

v3.10.0.1
Equity Incentive Plan (Tables)
 12 Months Ended
Dec. 31, 2018
Share Based Compensation Option And Incentive Plan [Abstract]  
Share-based Compensation, Stock Options, Activity [Table Text Block]
The following is a summary of stock option activity for the twelve months ended December 31, 2018 and December 31, 2017:
 
 
 
Number of Options
 
 
Weighted-
Average
Exercise Price
 
 
Weighted-Average
Contractual Life
(In Years)
 
Outstanding at December 31, 2016
 
 
1,509,711
 
 
$
2.85
 
 
 
5.04
 
Granted
 
 
568,450
 
 
 
1.39
 
 
 
9.41
 
Exercised
 
 
(61,078
)
 
 
0.67
 
 
 
 
 
Expired
 
 
(92,630
)
 
 
2.10
 
 
 
 
 
Forfeited
 
 
(31,450
)
 
 
2.99
 
 
 
 
 
Outstanding at December 31, 2017
 
 
1,893,003
 
 
$
2.49
 
 
 
5.40
 
Granted
 
 
415,500
 
 
 
0.57
 
 
 
9.23
 
Expired
 
 
(140,192
)
 
 
1.55
 
 
 
 
 
Forfeited
 
 
(92,158
)
 
 
1.03
 
 
 
 
 
Outstanding at December 31, 2018
 
 
2,076,153
 
 
$
2.28
 
 
 
6.51
 
Exercisable at December 31, 2018
 
 
1,493,386
 
 
$
2.81
 
 
 
5.57
 
Vested and Expected to Vest at December 31, 2018
 
 
2,076,153
 
 
 $
2.28
 
 
 
6.51
 
Schedule of Share-based Payment Award, Stock Options, Valuation Assumptions [Table Text Block]
For the twelve months ended December 31, 2018 and 2017, the fair value of each option grant has been estimated on the date of grant using the Black-Scholes Option Pricing Model with the following weighted-average assumptions: 
 
 
 
2018
 
 
2017
 
Risk-Free Interest Rate
 
 
1.82
%
 
 
1.82
%
Expected Life
 
 
8.01 years
 
 
 
7.25 years
 
Expected Volatility
 
 
158
%
 
 
170
%
Expected Dividend Yield
 
 
0
%
 
 
0
%
Schedule of Share-based Compensation, Restricted Stock and Restricted Stock Units Activity [Table Text Block]
The following is a summary of restricted stock activity for the twelve months ended December 31, 2018 and December 31, 2017: 
 
 
 
Number of 
Shares
 
 
Weighted-Average
Grant Date Fair

Value
 
 
Weighted-Average
Remaining

Recognition Period
 
Outstanding at December 31, 2016
 
 
-
 
 
$
-
 
 
 
 
 
Awarded
 
 
104,000
 
 
 
1.52
 
 
 
 
 
Forfeited
 
 
(1,000
)
 
 
1.52
 
 
 
 
 
Outstanding at December 31, 2017
 
 
103,000
 
 
$
1.52
 
 
 
 
 
Awarded
 
 
1,890,000
 
 
 
0.57
 
 
 
 
 
Released
 
 
(62,475
)
 
 
1.52
 
 
 
 
 
Forfeited
 
 
(108,393
)
 
 
0.60
 
 
 
 
 
Outstanding at December 31, 2018
 
 
1,822,132
 
 
$
0.59
 
 
 
2.25
 
Employee and Non Employee Service Share Based Compensation Allocation off Recognized Period Costs [Table Text Block]
The total stock-based compensation expense for employees and non-employees is included in the accompanying Consolidated Statements of Operations and as follows: 
 
 
 
Year Ended December 31,
 
 
 
2018
 
 
2017
 
Research and Development
 
$
255,505
 
 
$
193,688
 
General and Administrative
 
 
619,782
 
 
 
676,620
 
Total Stock-Based Compensation Expense
 
$
875,287
 
 
$
870,308