Quarterly report pursuant to Section 13 or 15(d)

Equity Incentive Plan (Details Textual)

v3.5.0.2
Equity Incentive Plan (Details Textual) - USD ($)
1 Months Ended 6 Months Ended 12 Months Ended
Jan. 25, 2016
Feb. 24, 2015
Jun. 30, 2016
Jun. 30, 2015
Dec. 31, 2015
Apr. 25, 2016
Mar. 29, 2016
Mar. 07, 2016
Jan. 31, 2016
Dec. 31, 2010
Share-based Compensation Arrangement by Share-based Payment Award, Compensation Cost [Line Items]                    
Employee Service Share-based Compensation, Nonvested Awards, Compensation Cost Not yet Recognized     $ 1,099,000 $ 832,000            
Employee Service Share-based Compensation, Nonvested Awards, Compensation Cost Not yet Recognized, Period for Recognition     2 years 8 months 16 days 3 years 4 months 17 days            
Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding And Exercisable Intrinsic Value     $ 1,076,000              
Share-based Compensation Arrangement by Share-based Payment Award, Options, Exercises in Period, Intrinsic Value     207,000   $ 123,000          
Share-based Compensation Arrangement by Share-based Payment Award, Options, Vested in Period, Fair Value     $ 474,000 $ 1,132,000            
Employee Stock Option [Member] | Jade Therapeutics [Member]                    
Share-based Compensation Arrangement by Share-based Payment Award, Compensation Cost [Line Items]                    
Share-based Compensation Arrangement by Share-based Payment Award, Number of Shares Available for Grant             114,438      
Employee Stock Option [Member] | Two Executive And Seven Members [Member]                    
Share-based Compensation Arrangement by Share-based Payment Award, Compensation Cost [Line Items]                    
Share-based Compensation Arrangement by Share-based Payment Award, Number of Shares Available for Grant 48,300                  
Share-based Compensation Arrangement by Share-based Payment Award, Award Vesting Rights vest 33.33% on the one-year anniversary of the grant date, and the remainder ratably over a 24-month period.                  
Employee Stock Option [Member] | Two Executive [Member] | Jade Therapeutics [Member]                    
Share-based Compensation Arrangement by Share-based Payment Award, Compensation Cost [Line Items]                    
Share-based Compensation Arrangement by Share-based Payment Award, Number of Shares Available for Grant               47,786    
Equity Incentive Plan 2005 [Member]                    
Share-based Compensation Arrangement by Share-based Payment Award, Compensation Cost [Line Items]                    
Share-based Compensation Arrangement by Share-based Payment Award, Number of Shares Authorized                   891,222
Equity Incentive Plan 2014 [Member]                    
Share-based Compensation Arrangement by Share-based Payment Award, Compensation Cost [Line Items]                    
Share-based Compensation Arrangement by Share-based Payment Award, Options, Exercises in Period     (86,765) (23,075)            
ESPP [Member]                    
Share-based Compensation Arrangement by Share-based Payment Award, Compensation Cost [Line Items]                    
Share-based Compensation Arrangement by Share-based Payment Award, Number of Shares Available for Grant     70,567              
2005 And 2014 Plan [Member]                    
Share-based Compensation Arrangement by Share-based Payment Award, Compensation Cost [Line Items]                    
Share-based Compensation Arrangement by Share-based Payment Award, Number of Shares Available for Grant     180,391              
2014 Plan [Member]                    
Share-based Compensation Arrangement by Share-based Payment Award, Compensation Cost [Line Items]                    
Share-based Compensation Arrangement by Share-based Payment Award, Number of Shares Available for Grant     1,034,888     41,732     1,034,888  
Excess Stock, Shares Authorized                 306,291  
2014 Plan [Member] | Employee Stock Option [Member]                    
Share-based Compensation Arrangement by Share-based Payment Award, Compensation Cost [Line Items]                    
Share-based Compensation Arrangement by Share-based Payment Award, Award Vesting Rights   vest 25% on the grant date, 25% on the one-year anniversary of the grant date, and the remaining 50% in 24 monthly equal installments thereafter.                
2014 Plan [Member] | Employee Stock Option [Member] | Two Executive And Seven Members [Member]                    
Share-based Compensation Arrangement by Share-based Payment Award, Compensation Cost [Line Items]                    
Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding And Exercisable Intrinsic Value   $ 350,000