Quarterly report pursuant to Section 13 or 15(d)

Equity Incentive Plan (Details Textual)

v3.4.0.3
Equity Incentive Plan (Details Textual) - USD ($)
1 Months Ended 3 Months Ended
Jan. 25, 2016
Feb. 24, 2015
Mar. 31, 2016
Mar. 31, 2015
Mar. 29, 2016
Mar. 07, 2016
Jan. 31, 2016
Dec. 31, 2010
Share-based Compensation Arrangement by Share-based Payment Award, Compensation Cost [Line Items]                
Employee Service Share-based Compensation, Nonvested Awards, Compensation Cost Not yet Recognized     $ 1,145,000 $ 911,000        
Employee Service Share-based Compensation, Nonvested Awards, Compensation Cost Not yet Recognized, Period for Recognition     3 years 3 years 7 months 17 days        
Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding And Exercisable Intrinsic Value     $ 1,562,000          
Share-based Compensation Arrangement by Share-based Payment Award, Options, Vested in Period, Fair Value     $ 375,747 $ 443,807        
Employee Stock Option [Member] | Jade Therapeutics [Member]                
Share-based Compensation Arrangement by Share-based Payment Award, Compensation Cost [Line Items]                
Share-based Compensation Arrangement by Share-based Payment Award, Number of Shares Available for Grant         114,438      
Employee Stock Option [Member] | Two Executive And Seven Members [Member]                
Share-based Compensation Arrangement by Share-based Payment Award, Compensation Cost [Line Items]                
Share-based Compensation Arrangement by Share-based Payment Award, Number of Shares Available for Grant 48,300              
Share-based Compensation Arrangement by Share-based Payment Award, Award Vesting Rights vest 33% on the one-year anniversary of the grant date and the remainder ratably over a 24-month period              
Employee Stock Option [Member] | Two Executive [Member] | Jade Therapeutics [Member]                
Share-based Compensation Arrangement by Share-based Payment Award, Compensation Cost [Line Items]                
Share-based Compensation Arrangement by Share-based Payment Award, Number of Shares Available for Grant           47,786    
Equity Incentive Plan 2005 [Member]                
Share-based Compensation Arrangement by Share-based Payment Award, Compensation Cost [Line Items]                
Share-based Compensation Arrangement by Share-based Payment Award, Number of Shares Authorized               891,222
ESPP [Member]                
Share-based Compensation Arrangement by Share-based Payment Award, Compensation Cost [Line Items]                
Share-based Compensation Arrangement by Share-based Payment Award, Number of Shares Available for Grant     70,567          
2005 And 2014 Plan [Member]                
Share-based Compensation Arrangement by Share-based Payment Award, Compensation Cost [Line Items]                
Share-based Compensation Arrangement by Share-based Payment Award, Number of Shares Available for Grant     209,761          
2014 Plan [Member]                
Share-based Compensation Arrangement by Share-based Payment Award, Compensation Cost [Line Items]                
Share-based Compensation Arrangement by Share-based Payment Award, Number of Shares Available for Grant     1,034,888       1,034,888  
Excess Stock, Shares Authorized             306,291  
2014 Plan [Member] | Employee Stock Option [Member]                
Share-based Compensation Arrangement by Share-based Payment Award, Compensation Cost [Line Items]                
Share-based Compensation Arrangement by Share-based Payment Award, Award Vesting Rights   vest 25% on the grant date, 25% on the one-year anniversary of the grant date, and the remaining 50% in 24 monthly equal installments thereafter            
2014 Plan [Member] | Employee Stock Option [Member] | Two Executive And Seven Members [Member]                
Share-based Compensation Arrangement by Share-based Payment Award, Compensation Cost [Line Items]                
Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding And Exercisable Intrinsic Value   $ 350,000