Annual report pursuant to Section 13 and 15(d)

Quarterly Financial Information (Unaudited) - Shareholders' equity (Details)

v3.22.2
Quarterly Financial Information (Unaudited) - Shareholders' equity (Details) - USD ($)
Dec. 31, 2021
Sep. 30, 2021
Jun. 30, 2021
Mar. 31, 2021
Dec. 31, 2020
Dec. 31, 2019
CONDENSED CONSOLIDATED STATEMENT OF STOCKHOLDERS' EQUITY            
Cumulative Effect of Change in Accounting Principle (Note 2) $ 14,579,048       $ 9,729,741 $ 6,622,455
Preferred Stock, Par or Stated Value Per Share $ 0.01       $ 0.01  
Common Stock, Par or Stated Value Per Share $ 0.01       $ 0.01  
Preferred Stock            
CONDENSED CONSOLIDATED STATEMENT OF STOCKHOLDERS' EQUITY            
Cumulative Effect of Change in Accounting Principle (Note 2) $ 0       $ 41 41
Common Stock            
CONDENSED CONSOLIDATED STATEMENT OF STOCKHOLDERS' EQUITY            
Cumulative Effect of Change in Accounting Principle (Note 2) 126,640       55,564 40,778
Additional Paid-In Capital            
CONDENSED CONSOLIDATED STATEMENT OF STOCKHOLDERS' EQUITY            
Cumulative Effect of Change in Accounting Principle (Note 2) 135,418,188       116,783,602 106,689,065
Accumulated Deficit            
CONDENSED CONSOLIDATED STATEMENT OF STOCKHOLDERS' EQUITY            
Cumulative Effect of Change in Accounting Principle (Note 2) (120,879,349)       (107,108,664) (100,246,894)
Accumulated Other Comprehensive Loss            
CONDENSED CONSOLIDATED STATEMENT OF STOCKHOLDERS' EQUITY            
Cumulative Effect of Change in Accounting Principle (Note 2) (86,431)       (802) $ 139,465
Correction in Accounting For Acquisitions And Subsequent Intangible Asset Impairment [Member]            
CONDENSED CONSOLIDATED STATEMENT OF STOCKHOLDERS' EQUITY            
Cumulative Effect of Change in Accounting Principle (Note 2) $ 14,579,048 $ 20,506,726 $ 13,680,473 $ 15,985,403 $ 9,729,741  
Preferred Stock, Par or Stated Value Per Share $ 0.01 $ 0.01 $ 0.01 $ 0.01 $ 0.01  
Common Stock, Par or Stated Value Per Share $ 0.01 $ 0.01 $ 0.01 $ 0.01 $ 0.01  
Correction in Accounting For Acquisitions And Subsequent Intangible Asset Impairment [Member] | Preferred Stock            
CONDENSED CONSOLIDATED STATEMENT OF STOCKHOLDERS' EQUITY            
Cumulative Effect of Change in Accounting Principle (Note 2)     $ 41 $ 41 $ 41  
Correction in Accounting For Acquisitions And Subsequent Intangible Asset Impairment [Member] | Common Stock            
CONDENSED CONSOLIDATED STATEMENT OF STOCKHOLDERS' EQUITY            
Cumulative Effect of Change in Accounting Principle (Note 2) $ 126,640 $ 126,193 70,979 70,979 55,564  
Correction in Accounting For Acquisitions And Subsequent Intangible Asset Impairment [Member] | Additional Paid-In Capital            
CONDENSED CONSOLIDATED STATEMENT OF STOCKHOLDERS' EQUITY            
Cumulative Effect of Change in Accounting Principle (Note 2) 135,418,188 135,137,530 125,286,886 125,023,994 116,783,602  
Correction in Accounting For Acquisitions And Subsequent Intangible Asset Impairment [Member] | Accumulated Deficit            
CONDENSED CONSOLIDATED STATEMENT OF STOCKHOLDERS' EQUITY            
Cumulative Effect of Change in Accounting Principle (Note 2) (120,879,349) (114,697,127) (111,662,297) (109,119,282) (107,108,664)  
Correction in Accounting For Acquisitions And Subsequent Intangible Asset Impairment [Member] | Accumulated Other Comprehensive Loss            
CONDENSED CONSOLIDATED STATEMENT OF STOCKHOLDERS' EQUITY            
Cumulative Effect of Change in Accounting Principle (Note 2) (86,431) (59,870) (15,136) 9,671 (802)  
Correction in Accounting For Acquisitions And Subsequent Intangible Asset Impairment [Member] | As reported            
CONDENSED CONSOLIDATED STATEMENT OF STOCKHOLDERS' EQUITY            
Cumulative Effect of Change in Accounting Principle (Note 2) 9,224,614 17,348,046 10,453,787 12,685,000 6,999,541  
Correction in Accounting For Acquisitions And Subsequent Intangible Asset Impairment [Member] | As reported | Preferred Stock            
CONDENSED CONSOLIDATED STATEMENT OF STOCKHOLDERS' EQUITY            
Cumulative Effect of Change in Accounting Principle (Note 2)     41 41 41  
Correction in Accounting For Acquisitions And Subsequent Intangible Asset Impairment [Member] | As reported | Common Stock            
CONDENSED CONSOLIDATED STATEMENT OF STOCKHOLDERS' EQUITY            
Cumulative Effect of Change in Accounting Principle (Note 2) 126,640 126,193 70,979 70,979 55,564  
Correction in Accounting For Acquisitions And Subsequent Intangible Asset Impairment [Member] | As reported | Additional Paid-In Capital            
CONDENSED CONSOLIDATED STATEMENT OF STOCKHOLDERS' EQUITY            
Cumulative Effect of Change in Accounting Principle (Note 2) 133,918,158 133,637,500 123,786,856 123,523,964 115,283,572  
Correction in Accounting For Acquisitions And Subsequent Intangible Asset Impairment [Member] | As reported | Accumulated Deficit            
CONDENSED CONSOLIDATED STATEMENT OF STOCKHOLDERS' EQUITY            
Cumulative Effect of Change in Accounting Principle (Note 2) (124,733,753) (116,355,777) (113,388,953) (110,919,655) (108,338,834)  
Correction in Accounting For Acquisitions And Subsequent Intangible Asset Impairment [Member] | As reported | Accumulated Other Comprehensive Loss            
CONDENSED CONSOLIDATED STATEMENT OF STOCKHOLDERS' EQUITY            
Cumulative Effect of Change in Accounting Principle (Note 2) (86,431) (59,870) (15,136) 9,671 $ (802)  
Correction in Accounting For Acquisitions And Subsequent Intangible Asset Impairment [Member] | 2021 Restatement Adjustment            
CONDENSED CONSOLIDATED STATEMENT OF STOCKHOLDERS' EQUITY            
Cumulative Effect of Change in Accounting Principle (Note 2) 2,624,234 428,480 496,486 570,203    
Correction in Accounting For Acquisitions And Subsequent Intangible Asset Impairment [Member] | 2021 Restatement Adjustment | Accumulated Deficit            
CONDENSED CONSOLIDATED STATEMENT OF STOCKHOLDERS' EQUITY            
Cumulative Effect of Change in Accounting Principle (Note 2) $ 2,624,234 428,480 496,486 570,203    
Correction in Accounting For Acquisitions And Subsequent Intangible Asset Impairment [Member] | 2020 restatements            
CONDENSED CONSOLIDATED STATEMENT OF STOCKHOLDERS' EQUITY            
Cumulative Effect of Change in Accounting Principle (Note 2)   2,730,200 2,730,200 2,730,200    
Correction in Accounting For Acquisitions And Subsequent Intangible Asset Impairment [Member] | 2020 restatements | Additional Paid-In Capital            
CONDENSED CONSOLIDATED STATEMENT OF STOCKHOLDERS' EQUITY            
Cumulative Effect of Change in Accounting Principle (Note 2)   1,500,030 1,500,030 1,500,030    
Correction in Accounting For Acquisitions And Subsequent Intangible Asset Impairment [Member] | 2020 restatements | Accumulated Deficit            
CONDENSED CONSOLIDATED STATEMENT OF STOCKHOLDERS' EQUITY            
Cumulative Effect of Change in Accounting Principle (Note 2)   $ 1,230,170 $ 1,230,170 $ 1,230,170