Exhibit 99.1

Lead Independent Director Charter

If the Chairman of the Board of EyeGate Pharmaceutical, Inc. (the “Company”) is also an employee of the Company or its subsidiaries, then the independent members of the Board of Directors will annually elect with a majority vote an independent director to serve in a lead capacity. Although elected annually, the Lead Independent Director is generally expected to serve for more than one year. The Lead Independent Director may be removed or replaced at any time with or without cause by a majority vote of the independent members of the Board of Directors.

For purposes of this Charter, “independent” means meeting the requirements for independent directors under Nasdaq Stock Market Listing Rule 5605(a)(2) and Rule 10A-3 under the Securities Exchange Act of 1934, as amended.

The Lead Independent Director coordinates the activities of the other independent Directors and performs such other duties and responsibilities as the Board of Directors may determine.

The specific powers and responsibilities of the Lead Independent Director are as follows:

Executive Sessions

Preside at all meetings of the Board of Directors at which the Chairman is not present, including executive sessions of the independent Directors.

Call Meetings of Independent Directors

Has the authority to call meetings of the independent Directors.

Chairman Liaison

Serve as the principal liaison between the Chairman and the independent Directors.

Approve Board Information, Agendas and Schedules

Approve meeting agendas for the Board of Directors.

Approve the frequency of Board of Directors meetings and meeting schedules, assuring there is sufficient time for discussion of all agenda items.

Recommend Committee Membership and Chair

Recommend to the Nominating and Corporate Governance Committee and to the Chairman, selection for the membership and chairman position for each Board committee.

Recommend Director Candidates

Interview, along with the chair of the Nominating and Corporate Governance Committee, all Director candidates and make recommendations to the Nominating and Corporate Governance Committee.

Stockholder Communication

Be available, when appropriate, for consultation and direct communication with stockholders.

Retain Advisors and Consultants

Has the authority to retain outside advisors and consultants who report directly to the Board of Directors on Board-wide issues.

Compensation

Receive additional compensation as determined from time to time by the Board of Directors, upon recommendation of the Compensation Committee.

Advisors

To the extent requested by the Lead Independent Director and where appropriate, counsel to the Company shall provide advice and counsel to the Lead Independent Director in fulfilling the Lead Independent Director's duties.

The Lead Independent Director may, at the Company's sole expense, select, retain and consult with outside counsel and other advisors as the Lead Independent Director deems appropriate.

Charter Review

On an annual basis, the Lead Independent Director shall review this Charter and recommend to the Board of Directors for approval any modifications or changes.